Pseudomonas aeruginosa PAO1, PA4218 (ampP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA4218
Name
ampP
Synonym: fptX
Replicon chromosome
Genomic location 4721614 - 4722858 (- strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_252908.1
GI 15599414
Affymetrix PA4218_at
Entrez 880532
GenBank AAG07606.1
INSDC AAG07606.1
NCBI Locus Tag PA4218
protein_id(GenBank) gb|AAG07606.1|AE004838_10|gnl|PseudoCAP|PA4218
TIGR NTL03PA04219
UniParc UPI00000C5C78
UniProtKB Acc Q9HWG8
UniProtKB ID Q9HWG8_PSEAE
UniRef100 UniRef100_A0A080VN97
UniRef50 UniRef50_Q2RW46
UniRef90 UniRef90_A6UZN1

Product

Feature Type CDS
Coding Frame 1
Product Name
AmpP
Product Name Confidence: Class 3
Evidence for Translation
Charge (pH 7) 9.95
Kyte-Doolittle Hydrophobicity Value 0.739
Molecular Weight (kDa) 43.2
Isoelectric Point (pI) 9.40

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 236 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001489 (319 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4218
Search term: ampP
Search term: AmpP

Transposon Insertions in PAO1

Type ISlacZ/hah insertion site
Mutant ID UWGC: 9485
Genomic Position 4721810
Position in ORF 197(1245)
Reference 14617778
Type ISlacZ/hah insertion site
Mutant ID UWGC: 20445
Genomic Position 4722688
Position in ORF 1075(1245)
Reference 14617778

Transposon Insertions in Orthologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res. 2005 Feb;15(2):321-9
PubMed ID: 15687295
Pseudomonas aeruginosa β-lactamase induction requires two permeases, AmpG and AmpP.
Kong KF, Aguila A, Schneper L, Mathee K
BMC Microbiol. 2010 Dec;10
PubMed ID: 21192796
Identification of rhtX and fptX, novel genes encoding proteins that show homology and function in the utilization of the siderophores rhizobactin 1021 by Sinorhizobium meliloti and pyochelin by Pseudomonas aeruginosa, respectively.
Cuív PO, Clarke P, Lynch D, O'Connell M
J. Bacteriol. 2004 May;186(10):2996-3005
PubMed ID: 15126460