Pseudomonas aeruginosa PAO1, PA4219 (ampO)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4219
Name
ampO
Synonym: yfpB
Replicon chromosome
Genomic location 4722851 - 4724035 (- strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252909
GI 15599415
Affymetrix PA4219_at
Entrez 880533
GenBank AAG07607.1
NCBI Locus Tag PA4219
protein_id(GenBank) gb|AAG07607.1|AE004838_11|gnl|PseudoCAP|PA4219
TIGR NTL03PA04220
UniProtKB Acc P42514
UniProtKB ID Y4219_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
AmpO
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 20.69
Kyte-Doolittle Hydrophobicity Value 0.494
Molecular Weight (kDa) 42.2
Isoelectric Point (pI) 11.80

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 72 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001488 (292 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4219
Search term: ampO
Search term: AmpO

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Pseudomonas aeruginosa β-lactamase induction requires two permeases, AmpG and AmpP.
Kong KF, Aguila A, Schneper L, Mathee K
BMC Microbiol. 2010 Dec;10
PubMed ID: 21192796