Pseudomonas aeruginosa PAO1, PA4297 (tadG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4297
Name
tadG
Synonym: tadG
Replicon chromosome
Genomic location 4821385 - 4823055 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_252987.1
GI 15599493
Affymetrix PA4297_at
Entrez 881605
GenBank AAG07685.1
INSDC AAG07685.1
NCBI Locus Tag PA4297
protein_id(GenBank) gb|AAG07685.1|AE004846_2|gnl|PseudoCAP|PA4297
TIGR NTL03PA04298
UniParc UPI00000C5CA2
UniProtKB Acc Q9HWA3
UniProtKB ID Q9HWA3_PSEAE
UniRef100 UniRef100_Q9HWA3
UniRef50 UniRef50_Q9HWA3
UniRef90 UniRef90_Q9HWA3

Product

Feature Type CDS
Coding Frame 1
Product Name
TadG
Product Name Confidence: Class 2
Synonyms TadG
Evidence for Translation
Charge (pH 7) -7.66
Kyte-Doolittle Hydrophobicity Value 0.464
Molecular Weight (kDa) 56.4
Isoelectric Point (pI) 4.79

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 33 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003898 (429 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4297
Search term: tadG
Search term: TadG

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
FppA, a novel Pseudomonas aeruginosa prepilin peptidase involved in assembly of type IVb pili.
de Bentzmann S, Aurouze M, Ball G, Filloux A
J Bacteriol 2006 Jul;188(13):4851-60
PubMed ID: 16788194
Mutation analysis of the flp operon in Actinobacillus actinomycetemcomitans.
Wang Y, Chen C
Gene 2005 May 23;351:61-71
PubMed ID: 15837433