Pseudomonas aeruginosa PAO1, PA4299 (tadD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4299
Name
tadD
Synonym: tadD
Replicon chromosome
Genomic location 4823387 - 4824124 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252989.1
GI 15599495
Affymetrix PA4299_at
DNASU PaCD00007864
Entrez 881552
GenBank AAG07687.1
INSDC AAG07687.1
NCBI Locus Tag PA4299
protein_id(GenBank) gb|AAG07687.1|AE004846_4|gnl|PseudoCAP|PA4299
TIGR NTL03PA04300
UniParc UPI00000C5CA4
UniProtKB Acc Q9HWA1
UniProtKB ID Y4299_PSEAE
UniRef100 UniRef100_Q9HWA1
UniRef50 UniRef50_Q9HWA1
UniRef90 UniRef90_Q9HWA1

Product

Feature Type CDS
Coding Frame 1
Product Name
TadD
Product Name Confidence: Class 2
Synonyms TadD
Evidence for Translation
Charge (pH 7) -1.15
Kyte-Doolittle Hydrophobicity Value -0.281
Molecular Weight (kDa) 26.6
Isoelectric Point (pI) 6.53

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 24 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003900 (425 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4299
Search term: tadD
Search term: TadD

Human Homologs

References

FppA, a novel Pseudomonas aeruginosa prepilin peptidase involved in assembly of type IVb pili.
de Bentzmann S, Aurouze M, Ball G, Filloux A
J Bacteriol 2006 Jul;188(13):4851-60
PubMed ID: 16788194
Mutation analysis of the flp operon in Actinobacillus actinomycetemcomitans.
Wang Y, Chen C
Gene 2005 May 23;351:61-71
PubMed ID: 15837433