Pseudomonas aeruginosa PAO1, PA4302 (tadA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4302
Name
tadA
Synonym: hvbA
Synonym: tadA
Replicon chromosome
Genomic location 4825923 - 4827188 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_252992.1
GI 15599498
Affymetrix PA4302_at
Entrez 881597
GenBank AAG07690.1
INSDC AAG07690.1
NCBI Locus Tag PA4302
protein_id(GenBank) gb|AAG07690.1|AE004846_7|gnl|PseudoCAP|PA4302
TIGR NTL03PA04303
UniParc UPI00000C5CA7
UniProtKB Acc Q9HW98
UniProtKB ID Q9HW98_PSEAE
UniRef100 UniRef100_W0YX56
UniRef50 UniRef50_Q7UXS5
UniRef90 UniRef90_W0YX56

Product

Feature Type CDS
Coding Frame 1
Product Name
TadA ATPase
Product Name Confidence: Class 2
Synonyms TadA ATPase
Evidence for Translation
Charge (pH 7) -7.96
Kyte-Doolittle Hydrophobicity Value -0.115
Molecular Weight (kDa) 46.8
Isoelectric Point (pI) 5.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 565 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003903 (475 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4302
Search term: tadA
Search term: TadA ATPase

Human Homologs

References

FppA, a novel Pseudomonas aeruginosa prepilin peptidase involved in assembly of type IVb pili.
de Bentzmann S, Aurouze M, Ball G, Filloux A
J Bacteriol 2006 Jul;188(13):4851-60
PubMed ID: 16788194
Mutation analysis of the flp operon in Actinobacillus actinomycetemcomitans.
Wang Y, Chen C
Gene 2005 May 23;351:61-71
PubMed ID: 15837433