Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4367
|
Name |
bifA
Synonym: bifA |
Replicon | chromosome |
Genomic location | 4894459 - 4896522 (+ strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
Comment | Overexpression of PA4367 impairs TTSS-mediated cytotoxicity |
RefSeq | NP_253057.1 |
GI | 15599563 |
Affymetrix | PA4367_at |
Entrez | 881428 |
GenBank | AAG07755.1 |
INSDC | AAG07755.1 |
NCBI Locus Tag | PA4367 |
protein_id(GenBank) | gb|AAG07755.1|AE004852_8|gnl|PseudoCAP|PA4367 |
TIGR | NTL03PA04368 |
UniParc | UPI00000C5CE4 |
UniProtKB Acc | Q9HW35 |
UniProtKB ID | Q9HW35_PSEAE |
UniRef100 | UniRef100_W0YZ94 |
UniRef50 | UniRef50_D7I4A9 |
UniRef90 | UniRef90_A0A0A8RHN1 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
BifA
|
Synonyms |
BifA |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -11.51 |
Kyte-Doolittle Hydrophobicity Value | -0.205 |
Molecular Weight (kDa) | 77.5 |
Isoelectric Point (pI) | 5.93 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
8ARV | HYDROLASE | 08/17/22 | Structure of the EAL domain of BifA from Pseudomonas aeruginosa | Pseudomonas aeruginosa PAO1 | 1.9 | X-RAY DIFFRACTION | 98.8 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 449 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG003960 (524 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4367
Search term: bifA
Search term: BifA
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
BifA, a cyclic-Di-GMP phosphodiesterase, inversely regulates biofilm formation and swarming motility by Pseudomonas aeruginosa PA14.
Kuchma SL, Brothers KM, Merritt JH, Liberati NT, Ausubel FM, O'Toole GA
J Bacteriol 2007 Nov;189(22):8165-78
PubMed ID: 17586641
|