Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4370
|
Name |
icmP
|
Replicon | chromosome |
Genomic location | 4898193 - 4899533 (+ strand) |
Transposon Mutants | 3 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 3 transposon mutants in orthologs |
RefSeq | NP_253060.1 |
GI | 15599566 |
Affymetrix | PA4370_at |
Entrez | 881386 |
GenBank | AAG07758.1 |
INSDC | AAG07758.1 |
NCBI Locus Tag | PA4370 |
protein_id(GenBank) | gb|AAG07758.1|AE004853_1|gnl|PseudoCAP|PA4370 |
TIGR | NTL03PA04371 |
UniParc | UPI00000C5CE7 |
UniProtKB Acc | Q9HW32 |
UniProtKB ID | Q9HW32_PSEAE |
UniRef100 | UniRef100_Q9HW32 |
UniRef50 | UniRef50_Q9HW32 |
UniRef90 | UniRef90_Q9HW32 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
Insulin-cleaving metalloproteinase outer membrane protein precursor
|
Synonyms |
outer membrane metalloproteinase precursor insulin-cleaving membrane proteinase ICMP |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected using LC-MS/MS (47.23 kDa, PMID:21751344)
|
Charge (pH 7) | -24.17 |
Kyte-Doolittle Hydrophobicity Value | -0.291 |
Molecular Weight (kDa) | 47.2 |
Isoelectric Point (pI) | 4.45 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
7XRX | METAL BINDING PROTEIN | 05/12/22 | insulin-cleaving membrane protease-ICMP | Pseudomonas aeruginosa PAO1 | 1.882 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 70 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG003962 (528 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4370
Search term: icmP
|
Characterization and purification of an outer membrane metalloproteinase from Pseudomonas aeruginosa with fibrinogenolytic activity.
Fricke B, Parchmann O, Kruse K, Rücknagel P, Schierhorn A, Menge S
Biochim Biophys Acta 1999 Aug 30;1454(3):236-50
PubMed ID: 10452958
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344
|