Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4374
|
Name |
mexV
|
Replicon | chromosome |
Genomic location | 4903466 - 4904596 (+ strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
RefSeq | NP_253064.1 |
GI | 15599570 |
Affymetrix | PA4374_at |
Entrez | 881374 |
GenBank | AAG07762.1 |
INSDC | AAG07762.1 |
NCBI Locus Tag | PA4374 |
protein_id(GenBank) | gb|AAG07762.1|AE004853_5|gnl|PseudoCAP|PA4374 |
TIGR | NTL03PA04375 |
UniParc | UPI00000C5CEB |
UniProtKB Acc | Q9HW28 |
UniProtKB ID | Q9HW28_PSEAE |
UniRef100 | UniRef100_X6YM01 |
UniRef50 | UniRef50_U5VAD4 |
UniRef90 | UniRef90_W0YYN3 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein MexV
|
Synonyms |
probable RND efflux membrane fusion protein precursor |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected using LC-MS/MS (40.87 kDa, PMID:21751344)
|
Charge (pH 7) | -3.50 |
Kyte-Doolittle Hydrophobicity Value | -0.019 |
Molecular Weight (kDa) | 40.9 |
Isoelectric Point (pI) | 5.35 |
Individual Mappings | |
Additional evidence for subcellular localization |
Identified using the Resistance Gene Identifier (RGI)
Model Name | Definition | Accession | Model Type (?) | SNP | Cutoff | Bit Score | Percent Identity | CARD Version |
MexV | MexV is the membrane fusion protein of the MexVW-OprM multidrug efflux complex. [PMID:12951344] | ARO:3003030 | protein homolog model | Perfect | 700.3 | 100.0 | 3.2.5 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 449 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001501 (811 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4374
Search term: mexV
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344
|
A new member of the tripartite multidrug efflux pumps, MexVW-OprM, in Pseudomonas aeruginosa.
Li Y, Mima T, Komori Y, Morita Y, Kuroda T, Mizushima T, Tsuchiya T
J Antimicrob Chemother 2003 Oct;52(4):572-5
PubMed ID: 12951344
|