Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4601
|
Name |
morA
|
Replicon | chromosome |
Genomic location | 5156368 - 5160615 (+ strand) |
Transposon Mutants | 10 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
Comment | absence of MorA led to a reduction in biofilm formation. MorA is membrane localized. |
RefSeq | NP_253291.1 |
GI | 15599797 |
Affymetrix | PA4601_at |
Entrez | 881084 |
GenBank | AAG07989.1 |
INSDC | AAG07989.1 |
NCBI Locus Tag | PA4601 |
protein_id(GenBank) | gb|AAG07989.1|AE004874_2|gnl|PseudoCAP|PA4601 |
TIGR | NTL03PA04602 |
UniParc | UPI00000C5D81 |
UniProtKB Acc | Q9HVI8 |
UniProtKB ID | Q9HVI8_PSEAE |
UniRef100 | UniRef100_Q9HVI8 |
UniRef50 | UniRef50_Q9HVI8 |
UniRef90 | UniRef90_Q9HVI8 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
motility regulator
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -22.55 |
Kyte-Doolittle Hydrophobicity Value | -0.275 |
Molecular Weight (kDa) | 159.6 |
Isoelectric Point (pI) | 6.01 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
4RNF | Transferase, Hydrolase | 10/24/14 | PaMorA tandem diguanylate cyclase - mutant phosphodiesterase, apo form | Pseudomonas aeruginosa PAO1 | 2.85 | X-RAY DIFFRACTION | 99.3 |
4RNI | HYDROLASE | 10/24/14 | PaMorA dimeric phosphodiesterase. apo form | Pseudomonas aeruginosa PAO1 | 2.17 | X-RAY DIFFRACTION | 99.3 |
4RNJ | HYDROLASE | 10/24/14 | PaMorA phosphodiesterase domain, apo form | Pseudomonas aeruginosa PAO1 | 2.32 | X-RAY DIFFRACTION | 99.3 |
4RNH | Transferase, Hydrolase | 10/24/14 | PaMorA tandem diguanylate cyclase - phosphodiesterase, c-di-GMP complex | Pseudomonas aeruginosa PAO1 | 2.45 | X-RAY DIFFRACTION | 99.8 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 520 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG004258 (973 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4601
Search term: morA
Search term: motility regulator
|
MorA defines a new class of regulators affecting flagellar development and biofilm formation in diverse Pseudomonas species.
Choy WK, Zhou L, Syn CK, Zhang LH, Swarup S
J Bacteriol 2004 Nov;186(21):7221-8
PubMed ID: 15489433
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|