Pseudomonas aeruginosa PAO1, PA4669 (ipk)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA4669
Name
ipk
Synonym: ychB
Replicon chromosome
Genomic location 5237393 - 5238241 (+ strand)

Cross-References

RefSeq NP_253358.1
GI 15599864
Affymetrix PA4669_ipk_at
DNASU PaCD00008026
Entrez 881380
GenBank AAG08056.1
INSDC CAA57570.1
NCBI Locus Tag PA4669
protein_id(GenBank) gb|AAG08056.1|AE004880_12|gnl|PseudoCAP|PA4669
TIGR NTL03PA04670
UniParc UPI000012D950
UniProtKB Acc P42805
UniProtKB ID ISPE_PSEAE
UniRef100 UniRef100_P42805
UniRef50 UniRef50_P42805
UniRef90 UniRef90_P42805

Product

Feature Type CDS
Coding Frame 1
Product Name
isopentenyl monophosphate kinase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -1.89
Kyte-Doolittle Hydrophobicity Value -0.078
Molecular Weight (kDa) 30.8
Isoelectric Point (pI) 6.61

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 512 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004319 (560 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4669
Search term: ipk

References

Isopentenyl diphosphate biosynthesis via a mevalonate-independent pathway: isopentenyl monophosphate kinase catalyzes the terminal enzymatic step.
Lange BM, Croteau R
Proc. Natl. Acad. Sci. U.S.A. 1999 Nov;96(24):13714-9
PubMed ID: 10570138
Regulation of the hemA gene during 5-aminolevulinic acid formation in Pseudomonas aeruginosa.
Hungerer C, Troup B, Römling U, Jahn D
J. Bacteriol. 1995 Mar;177(6):1435-43
PubMed ID: 7883699