Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4843
|
Name |
gcbA
|
Replicon | chromosome |
Genomic location | 5436079 - 5437707 (+ strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
RefSeq | NP_253530.1 |
GI | 15600036 |
Affymetrix | PA4843_at |
Entrez | 879632 |
GenBank | AAG08228.1 |
INSDC | AAG08228.1 |
NCBI Locus Tag | PA4843 |
protein_id(GenBank) | gb|AAG08228.1|AE004897_6|gnl|PseudoCAP|PA4843 |
TIGR | NTL03PA04844 |
UniParc | UPI00000C5E37 |
UniProtKB Acc | Q9HUW7 |
UniProtKB ID | Q9HUW7_PSEAE |
UniRef100 | UniRef100_W0Z042 |
UniRef50 | UniRef50_G8Q613 |
UniRef90 | UniRef90_B7V1Q5 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
GcbA
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -6.75 |
Kyte-Doolittle Hydrophobicity Value | -0.406 |
Molecular Weight (kDa) | 61.6 |
Isoelectric Point (pI) | 6.34 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 601 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG004473 (530 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4843
Search term: gcbA
Search term: GcbA
|
Identification of a novel response regulator required for the swarmer-to-stalked-cell transition in Caulobacter crescentus.
Hecht GB, Newton A
J Bacteriol 1995 Nov;177(21):6223-9
PubMed ID: 7592388
|
ChIP-Seq and RNA-Seq reveal an AmrZ-mediated mechanism for cyclic di-GMP synthesis and biofilm development by Pseudomonas aeruginosa.
Jones CJ, Newsom D, Kelly B, Irie Y, Jennings LK, Xu B, Limoli DH, Harrison JJ, Parsek MR, White P, Wozniak DJ
PLoS Pathog 2014 Mar;10(3):e1003984
PubMed ID: 24603766
|
The Pseudomonas aeruginosa diguanylate cyclase GcbA, a homolog of P. fluorescens GcbA, promotes initial attachment to surfaces, but not biofilm formation, via regulation of motility.
Petrova OE, Cherny KE, Sauer K
J Bacteriol 2014 Aug;196(15):2827-41
PubMed ID: 24891445
|
The diguanylate cyclase GcbA facilitates Pseudomonas aeruginosa biofilm dispersion by activating BdlA.
Petrova OE, Cherny KE, Sauer K
J Bacteriol 2015 Jan 1;197(1):174-87
PubMed ID: 25331436
|