Pseudomonas aeruginosa PAO1, PA4903

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4903
Name
Synonym: vanK
Replicon chromosome
Genomic location 5501338 - 5502672 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs
Commenttranscription induced by vanillate

Cross-References

RefSeq NP_253590.1
GI 15600096
Affymetrix PA4903_at
Entrez 882268
GenBank AAG08288.1
INSDC AAG08288.1
NCBI Locus Tag PA4903
protein_id(GenBank) gb|AAG08288.1|AE004903_6|gnl|PseudoCAP|PA4903
TIGR NTL03PA04904
UniParc UPI00000C5E6D
UniProtKB Acc Q9HUR0
UniProtKB ID Q9HUR0_PSEAE
UniRef100 UniRef100_Q9HUR0
UniRef50 UniRef50_O24842
UniRef90 UniRef90_A0A081HRY5

Product

Feature Type CDS
Coding Frame 1
Product Name
probable major facilitator superfamily (MFS) transporter
Product Name Confidence: Class 3
Synonyms probable MFS transporter
Evidence for Translation
Charge (pH 7) 13.02
Kyte-Doolittle Hydrophobicity Value 0.845
Molecular Weight (kDa) 46.2
Isoelectric Point (pI) 10.53

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 355 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004525 (370 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4903

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295