Pseudomonas aeruginosa PAO1, PA4910

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4910
Name
Replicon chromosome
Genomic location 5508682 - 5509554 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253597.1
GI 15600103
Affymetrix PA4910_at
Entrez 878157
GenBank AAG08295.1
INSDC AAG08295.1
NCBI Locus Tag PA4910
protein_id(GenBank) gb|AAG08295.1|AE004904_3|gnl|PseudoCAP|PA4910
TIGR NTL03PA04911
UniParc UPI00000C5E74
UniProtKB Acc Q9HUQ3
UniProtKB ID Q9HUQ3_PSEAE
UniRef100 UniRef100_W0YUK6
UniRef50 UniRef50_G8Q4Y5
UniRef90 UniRef90_A0A024HQ24

Product

Feature Type CDS
Coding Frame 1
Product Name
branched chain amino acid ABC transporter ATP binding protein
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -7.23
Kyte-Doolittle Hydrophobicity Value -0.049
Molecular Weight (kDa) 32.2
Isoelectric Point (pI) 5.91

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004529 (504 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4910

Human Homologs

Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily A member 13 [Source:HGNC Symbol;Acc:HGNC:14638]
E-value: 4.0e-17
Percent Identity: 27.5
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily A member 13 [Source:HGNC Symbol;Acc:HGNC:14638]
E-value: 4.0e-17
Percent Identity: 27.5
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily A member 13 [Source:HGNC Symbol;Acc:HGNC:14638]
E-value: 4.0e-17
Percent Identity: 27.5

References

Cloning, nucleotide sequences, and identification of products of the Pseudomonas aeruginosa PAO bra genes, which encode the high-affinity branched-chain amino acid transport system.
Hoshino T, Kose K
J Bacteriol 1990 Oct;172(10):5531-9
PubMed ID: 2120183