Pseudomonas aeruginosa PAO1, PA4971 (aspP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4971
Name
aspP
Synonym: yqiE
Replicon chromosome
Genomic location 5580102 - 5580719 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253658.1
GI 15600164
Affymetrix PA4971_at
DNASU PaCD00008150
Entrez 879756
GenBank AAG08356.1
INSDC AAG08356.1
NCBI Locus Tag PA4971
protein_id(GenBank) gb|AAG08356.1|AE004910_3|gnl|PseudoCAP|PA4971
TIGR NTL03PA04972
UniParc UPI00000C5EA2
UniProtKB Acc Q9HUJ4
UniProtKB ID Q9HUJ4_PSEAE
UniRef100 UniRef100_Q9HUJ4
UniRef50 UniRef50_A0A085J9E3
UniRef90 UniRef90_Q9HUJ4

Product

Feature Type CDS
Coding Frame 1
Product Name
adenosine diphosphate sugar pyrophosphatase
Product Name Confidence: Class 2
Synonyms ASPPase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -10.67
Kyte-Doolittle Hydrophobicity Value -0.229
Molecular Weight (kDa) 23.1
Isoelectric Point (pI) 4.70

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 403 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004586 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4971
Search term: aspP

Human Homologs

References

Adenosine diphosphate sugar pyrophosphatase prevents glycogen biosynthesis in Escherichia coli.
Moreno-Bruna B, Baroja-Fernández E, Muñoz FJ, Bastarrica-Berasategui A, Zandueta-Criado A, Rodriguez-López M, Lasa I, Akazawa T, Pozueta-Romero J
Proc Natl Acad Sci U S A 2001 Jul 3;98(14):8128-32
PubMed ID: 11416161