Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA5002
|
Name |
dnpA
|
Replicon | chromosome |
Genomic location | 5619608 - 5621026 (- strand) |
Transposon Mutants | 1 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
Comment |
RefSeq | NP_253689.1 |
GI | 15600195 |
Affymetrix | PA5002_at |
Entrez | 881666 |
GenBank | AAG08387.1 |
INSDC | AAG08387.1 |
NCBI Locus Tag | PA5002 |
protein_id(GenBank) | gb|AAG08387.1|AE004913_2|gnl|PseudoCAP|PA5002 |
TIGR | NTL03PA05003 |
UniParc | UPI00000C5EBF |
UniProtKB Acc | Q9HUG3 |
UniProtKB ID | Q9HUG3_PSEAE |
UniRef100 | UniRef100_Q9HUG3 |
UniRef50 | UniRef50_Q87VE8 |
UniRef90 | UniRef90_Q9HUG3 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
de-N-acetylase involved in persistence, DnpA
|
Synonyms |
hypothetical protein |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | 6.99 |
Kyte-Doolittle Hydrophobicity Value | -0.270 |
Molecular Weight (kDa) | 53.6 |
Isoelectric Point (pI) | 8.61 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 9 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG004610 (515 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA5002
Search term: dnpA
Search term: de-N-acetylase involved in persistence, DnpA
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
A putative de-N-acetylase of the PIG-L superfamily affects fluoroquinolone tolerance in Pseudomonas aeruginosa.
Liebens V, Defraine V, Van der Leyden A, De Groote VN, Fierro C, Beullens S, Verstraeten N, Kint C, Jans A, Frangipani E, Visca P, Marchal K, Versées W, Fauvart M, Michiels J
Pathog Dis 2014 Jun;71(1):39-54
PubMed ID: 24692291
|
The Putative De-N-acetylase DnpA Contributes to Intracellular and Biofilm-Associated Persistence of Pseudomonas aeruginosa Exposed to Fluoroquinolones.
Khandekar S, Liebens V, Fauvart M, Tulkens PM, Michiels J, Van Bambeke F
Front Microbiol 2018;9:1455
PubMed ID: 30042739
|