Pseudomonas aeruginosa PAO1, PA5004 (wapH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5004
Name
wapH
Replicon chromosome
Genomic location 5621920 - 5623056 (- strand)
Transposon Mutants in orthologs 5 transposon mutants in orthologs

Cross-References

RefSeq NP_253691.1
GI 15600197
Affymetrix PA5004_at
DNASU PaCD00008160
Entrez 881614
GenBank AAG08389.1
INSDC AAG08389.1
NCBI Locus Tag PA5004
protein_id(GenBank) gb|AAG08389.1|AE004913_4|gnl|PseudoCAP|PA5004
TIGR NTL03PA05005
UniParc UPI00000C5EC1
UniProtKB Acc Q9HUG1
UniProtKB ID Q9HUG1_PSEAE
UniRef100 UniRef100_S0HHK0
UniRef50 UniRef50_B9TD52
UniRef90 UniRef90_W0YY79

Product

Feature Type CDS
Coding Frame 1
Product Name
WapH
Product Name Confidence: Class 1
Synonyms probable glycosyl transferase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 6.43
Kyte-Doolittle Hydrophobicity Value -0.032
Molecular Weight (kDa) 42.2
Isoelectric Point (pI) 8.48

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 594 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001311 (2094 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5004
Search term: wapH
Search term: WapH

Human Homologs

References

A Mig-14-like protein (PA5003) affects antimicrobial peptide recognition in Pseudomonas aeruginosa.
Jochumsen N, Liu Y, Molin S, Folkesson A
Microbiology (Reading) 2011 Sep;157(Pt 9):2647-2657
PubMed ID: 21700666