Pseudomonas aeruginosa PAO1, PA5007 (wapG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5007
Name
wapG
Synonym: inaA
Synonym: waaQ
Synonym: wapQ
Replicon chromosome
Genomic location 5626376 - 5627134 (- strand)
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253694.1
GI 15600200
Affymetrix PA5007_at
Entrez 881608
GenBank AAG08392.1
INSDC AAG08392.1
NCBI Locus Tag PA5007
protein_id(GenBank) gb|AAG08392.1|AE004913_7|gnl|PseudoCAP|PA5007
TIGR NTL03PA05008
UniParc UPI00000C5EC4
UniProtKB Acc Q9HUF8
UniProtKB ID Q9HUF8_PSEAE
UniRef100 UniRef100_Q9HUF8
UniRef50 UniRef50_T2H094
UniRef90 UniRef90_B7V399

Product

Feature Type CDS
Coding Frame 1
Product Name
WapG
Product Name Confidence: Class 1
Synonyms WaaQ
hypothetical protein
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -0.13
Kyte-Doolittle Hydrophobicity Value -0.583
Molecular Weight (kDa) 29.4
Isoelectric Point (pI) 6.96

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 18 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004614 (532 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5007
Search term: wapG
Search term: WapG

Human Homologs

References

Lipopolysaccharide core phosphates are required for viability and intrinsic drug resistance in Pseudomonas aeruginosa.
Walsh AG, Matewish MJ, Burrows LL, Monteiro MA, Perry MB, Lam JS
Mol Microbiol 2000 Feb;35(4):718-27
PubMed ID: 10692150
Lipopolysaccharide (LPS) inner-core phosphates are required for complete LPS synthesis and transport to the outer membrane in Pseudomonas aeruginosa PAO1.
Delucia AM, Six DA, Caughlan RE, Gee P, Hunt I, Lam JS, Dean CR
mBio 2011;2(4)
PubMed ID: 21810964