Pseudomonas aeruginosa PAO1, PA5169 (dctM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5169
Name
dctM
Replicon chromosome
Genomic location 5818831 - 5820114 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_253856.1
GI 15600362
Affymetrix PA5169_at
Entrez 877773
GenBank AAG08554.1
INSDC AAG08554.1
NCBI Locus Tag PA5169
protein_id(GenBank) gb|AAG08554.1|AE004929_9|gnl|PseudoCAP|PA5169
TIGR NTL03PA05170
UniParc UPI00000C5F36
UniProtKB Acc Q9HU16
UniProtKB ID Q9HU16_PSEAE
UniRef100 UniRef100_W0Z2Y9
UniRef50 UniRef50_Q5P2I3
UniRef90 UniRef90_A6VDU0

Product

Feature Type CDS
Coding Frame 1
Product Name
DctM
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 3.83
Kyte-Doolittle Hydrophobicity Value 1.293
Molecular Weight (kDa) 45.2
Isoelectric Point (pI) 8.60

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 335 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000853 (789 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5169
Search term: dctM
Search term: DctM

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Identification of C(4)-dicarboxylate transport systems in Pseudomonas aeruginosa PAO1.
Valentini M, Storelli N, Lapouge K
J Bacteriol 2011 Sep;193(17):4307-16
PubMed ID: 21725012