Pseudomonas aeruginosa PAO1, PA5276 (lppL)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5276
Name
lppL
Replicon chromosome
Genomic location 5941336 - 5941476 (+ strand)

Cross-References

RefSeq NP_253963.1
GI 15600469
Affymetrix PA5276_lppL_i_at
Entrez 877754
GenBank AAG08661.1
INSDC AAG08661.1
NCBI Locus Tag PA5276
protein_id(GenBank) gb|AAG08661.1|AE004940_5|gnl|PseudoCAP|PA5276
TIGR NTL03PA05277
UniParc UPI000012E870
UniProtKB Acc P17323
UniProtKB ID LPPL_PSEAE
UniRef100 UniRef100_P17323
UniRef50 UniRef50_P17323
UniRef90 UniRef90_P17323

Product

Feature Type CDS
Coding Frame 1
Product Name
Lipopeptide LppL precursor
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 3.19
Kyte-Doolittle Hydrophobicity Value -0.163
Molecular Weight (kDa) 5.1
Isoelectric Point (pI) 9.75

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 1
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 5 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004854 (508 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5276
Search term: lppL

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
A lipopeptide-encoding sequence upstream from the lysA gene of Pseudomonas aeruginosa.
Jann A, Cavard D, Martin C, Cami B, Patte JC
Mol Microbiol 1990 Apr;4(4):677-82
PubMed ID: 2112674