Pseudomonas aeruginosa PAO1, PA5292 (pchP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5292
Name
pchP
Synonym: pcP
Replicon chromosome
Genomic location 5957208 - 5958257 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253979.1
GI 15600485
Affymetrix PA5292_at
Entrez 877730
GenBank AAG08677.1
INSDC AAG08677.1
NCBI Locus Tag PA5292
protein_id(GenBank) gb|AAG08677.1|AE004941_10|gnl|PseudoCAP|PA5292
TIGR NTL03PA05293
UniParc UPI00000C5F8F
UniProtKB Acc Q9HTR2
UniProtKB ID Q9HTR2_PSEAE
UniRef100 UniRef100_Q9HTR2
UniRef50 UniRef50_Q9HTR2
UniRef90 UniRef90_Q9HTR2

Product

Feature Type CDS
Coding Frame 1
Product Name
phosphorylcholine phosphatase
Product Name Confidence: Class 1
Synonyms phosphochlorylcholine phosphatase
Evidence for Translation
Charge (pH 7) -3.86
Kyte-Doolittle Hydrophobicity Value -0.267
Molecular Weight (kDa) 39.1
Isoelectric Point (pI) 5.76

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Periplasmic Class 1
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4AS3 HYDROLASE 04/27/12 Pseudomonas Aeruginosa Phosphorylcholine Phosphatase. Orthorhombic form PSEUDOMONAS AERUGINOSA 2.4 X-RAY DIFFRACTION 100.0
4AS2 HYDROLASE 04/27/12 Pseudomonas Aeruginosa Phosphorylcholine Phosphatase. Monoclinic form PSEUDOMONAS AERUGINOSA 2.12 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 21 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004868 (478 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5292
Search term: pchP

Human Homologs

References

Identification, cloning, and expression of Pseudomonas aeruginosa phosphorylcholine phosphatase gene.
Massimelli MJ, Beassoni PR, Forrellad MA, Barra JL, Garrido MN, Domenech CE, Lisa AT
Curr Microbiol 2005 May;50(5):251-6
PubMed ID: 15886911