Pseudomonas aeruginosa PAO1, PA5301 (pauR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5301
Name
pauR
Synonym: ycjC
Replicon chromosome
Genomic location 5969987 - 5970535 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253988.1
GI 15600494
Affymetrix PA5301_at
DNASU PaCD00008289
Entrez 878484
GenBank AAG08686.1
INSDC AAG08686.1
NCBI Locus Tag PA5301
protein_id(GenBank) gb|AAG08686.1|AE004943_2|gnl|PseudoCAP|PA5301
TIGR NTL03PA05302
UniParc UPI00000C5F96
UniProtKB Acc Q9HTQ3
UniProtKB ID Q9HTQ3_PSEAE
UniRef100 UniRef100_W0Z073
UniRef50 UniRef50_O31273
UniRef90 UniRef90_A6VEA6

Product

Feature Type CDS
Coding Frame 1
Product Name
PauR
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -4.04
Kyte-Doolittle Hydrophobicity Value -0.292
Molecular Weight (kDa) 19.9
Isoelectric Point (pI) 5.32

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 322 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004875 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5301
Search term: pauR
Search term: PauR

Human Homologs

References

Functional characterization of seven γ-Glutamylpolyamine synthetase genes and the bauRABCD locus for polyamine and β-Alanine utilization in Pseudomonas aeruginosa PAO1.
Yao X, He W, Lu CD
J. Bacteriol. 2011 Aug;193(15):3923-30
PubMed ID: 21622750
Molecular characterization of PauR and its role in control of putrescine and cadaverine catabolism through the γ-glutamylation pathway in Pseudomonas aeruginosa PAO1.
Chou HT, Li JY, Peng YC, Lu CD
J Bacteriol 2013 Sep;195(17):3906-13
PubMed ID: 23794626