Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA5398
|
Name |
dgcA
Synonym: dgcA |
Replicon | chromosome |
Genomic location | 6075880 - 6077940 (+ strand) |
Transposon Mutants | 12 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
Comment | Strains with deletions in dgcA are unable to grow on choline, glycine betaine, or dimethylglcycine but are able to utilize sarcosine. NMR analysis shows buildup of labeled dimethylglycine when dgcA mutants are given labeled choline. Presumed to function with DgcB (PA5399). |
RefSeq | NP_254085.1 |
GI | 15600591 |
Affymetrix | PA5398_at |
Entrez | 878122 |
GenBank | AAG08783.1 |
INSDC | AAG08783.1 |
NCBI Locus Tag | PA5398 |
protein_id(GenBank) | gb|AAG08783.1|AE004952_5|gnl|PseudoCAP|PA5398 |
TIGR | NTL03PA05399 |
UniParc | UPI00000C5FE3 |
UniProtKB Acc | Q9HTG6 |
UniProtKB ID | Q9HTG6_PSEAE |
UniRef100 | UniRef100_Q9HTG6 |
UniRef50 | UniRef50_Q9HTG6 |
UniRef90 | UniRef90_Q9HTG6 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
DgcA, Dimethylglycine catabolism
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | -13.28 |
Kyte-Doolittle Hydrophobicity Value | -0.216 |
Molecular Weight (kDa) | 75.7 |
Isoelectric Point (pI) | 5.89 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 509 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG004955 (510 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA5398
Search term: dgcA
Search term: DgcA, Dimethylglycine catabolism
|
Identification of two gene clusters and a transcriptional regulator required for Pseudomonas aeruginosa glycine betaine catabolism.
Wargo MJ, Szwergold BS, Hogan DA
J Bacteriol 2008 Apr;190(8):2690-9
PubMed ID: 17951379
|