Pseudomonas aeruginosa PAO1, PA5413 (ltaA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5413
Name
ltaA
Replicon chromosome
Genomic location 6092046 - 6093086 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_254100.1
GI 15600606
Affymetrix PA5413_ltaA_at
Entrez 880064
GenBank AAG08798.1
INSDC AAG08798.1
NCBI Locus Tag PA5413
protein_id(GenBank) gb|AAG08798.1|AE004953_12|gnl|PseudoCAP|PA5413
TIGR NTL03PA05414
UniParc UPI000012E999
UniProtKB Acc Q9HTF1
UniProtKB ID LTAE_PSEAE
UniRef100 UniRef100_Q9HTF1
UniRef50 UniRef50_O50584
UniRef90 UniRef90_Q9HTF1

Product

Feature Type CDS
Coding Frame 1
Product Name
low specificity l-threonine aldolase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -10.43
Kyte-Doolittle Hydrophobicity Value -0.092
Molecular Weight (kDa) 38.2
Isoelectric Point (pI) 5.00

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 320 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000869 (996 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5413
Search term: ltaA

Human Homologs

References

Gene cloning, nucleotide sequencing, and purification and characterization of the low-specificity L-threonine aldolase from Pseudomonas sp. strain NCIMB 10558.
Liu JQ, Ito S, Dairi T, Itoh N, Kataoka M, Shimizu S, Yamada H
Appl Environ Microbiol 1998 Feb;64(2):549-54
PubMed ID: 9464392