Pseudomonas aeruginosa PAO1, PA5508 (pauA7)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5508
Name
pauA7
Replicon chromosome
Genomic location 6199567 - 6200898 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_254195.1
GI 15600701
Affymetrix PA5508_at
Entrez 878661
GenBank AAG08893.1
INSDC AAG08893.1
NCBI Locus Tag PA5508
protein_id(GenBank) gb|AAG08893.1|AE004963_6|gnl|PseudoCAP|PA5508
TIGR NTL03PA05509
UniParc UPI00000C6043
UniProtKB Acc Q9HT65
UniProtKB ID Q9HT65_PSEAE
UniRef100 UniRef100_Q9HT65
UniRef50 UniRef50_G8PXR2
UniRef90 UniRef90_Q9HT65

Product

Feature Type CDS
Coding Frame 1
Product Name
Glutamylpolyamine synthetase homologue
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -7.95
Kyte-Doolittle Hydrophobicity Value -0.136
Molecular Weight (kDa) 47.9
Isoelectric Point (pI) 6.02

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4HPP LIGASE 10/24/12 Crystal structure of novel glutamine synthase homolog Pseudomonas aeruginosa 2.5 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 568 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005046 (364 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5508
Search term: pauA7

Human Homologs

References

Functional characterization of seven γ-Glutamylpolyamine synthetase genes and the bauRABCD locus for polyamine and β-Alanine utilization in Pseudomonas aeruginosa PAO1.
Yao X, He W, Lu CD
J. Bacteriol. 2011 Aug;193(15):3923-30
PubMed ID: 21622750