Pseudomonas aeruginosa PAO1, PA0001 (dnaA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA0001
Name
dnaA
Replicon chromosome
Genomic location 483 - 2027 (+ strand)

Cross-References

RefSeq NP_064721.1
GI 15595199
Affymetrix PA0001_dnaA_at
Entrez 878417
GenBank AAG03391.1
INSDC AAG03391.1
NCBI Locus Tag PA0001
protein_id(GenBank) gb|AAG03391.1|AE004440_1|gnl|PseudoCAP|PA0001
TIGR NTL03PA00002
UniParc UPI0000129539
UniProtKB Acc Q9I7C5
UniProtKB ID DNAA_PSEAE
UniRef100 UniRef100_B7V0N6
UniRef50 UniRef50_P29440
UniRef90 UniRef90_B7V0N6

Product

Feature Type CDS
Coding Frame 1
Product Name
chromosomal replication initiator protein DnaA
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 6.33
Kyte-Doolittle Hydrophobicity Value -0.286
Molecular Weight (kDa) 57.7
Isoelectric Point (pI) 8.88

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 584 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000001 (554 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0001
Search term: dnaA

References

The nucleotide sequence of the dnaA gene and the first part of the dnaN gene of Escherichia coli K-12.
Hansen EB, Hansen FG, von Meyenburg K
Nucleic Acids Res 1982 Nov 25;10(22):7373-85
PubMed ID: 6296774
Structural analysis of the dnaA and dnaN genes of Escherichia coli.
Ohmori H, Kimura M, Nagata T, Sakakibara Y
Gene 1984 May;28(2):159-70
PubMed ID: 6234204
The E. coli dnaA initiation protein: a protein for all seasons.
Georgopoulos C
Trends Genet 1989 Oct;5(10):319-21
PubMed ID: 2558436
Pseudomonas chromosomal replication origins: a bacterial class distinct from Escherichia coli-type origins.
Yee TW, Smith DW
Proc Natl Acad Sci U S A 1990 Feb;87(4):1278-82
PubMed ID: 2106132