Pseudomonas fluorescens Pf0-1, Pfl01_0623 (gcbA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas fluorescens Pf0-1
GCF_000012445.1|latest
Locus Tag
Pfl01_0623
Name
gcbA
Replicon chromosome
Genomic location 732894 - 734564 (- strand)

Cross-References

RefSeq YP_346356.1
GI 77456851
Entrez 3712380
INSDC ABA72367.1
NCBI Locus Tag Pfl01_0623
UniParc UPI0000387762
UniProtKB Acc Q3KIN9
UniProtKB ID Q3KIN9_PSEPF
UniRef100 UniRef100_Q3KIN9
UniRef50 UniRef50_G8Q613
UniRef90 UniRef90_G8Q613

Product

Feature Type CDS
Coding Frame 1
Product Name
di-guanylate cyclase promoting biofilm, GcbA
Product Name Confidence: Class 1
Synonyms response regulator receiver modulated diguanylate cyclase
Evidence for Translation
Charge (pH 7) -7.51
Kyte-Doolittle Hydrophobicity Value -0.346
Molecular Weight (kDa) 62927.9
Isoelectric Point (pI) 6.30

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004473 (530 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Pfl01_0623
Search term: gcbA

Human Homologs

References

Systematic analysis of diguanylate cyclases that promote biofilm formation by Pseudomonas fluorescens Pf0-1.
Newell PD, Yoshioka S, Hvorecny KL, Monds RD, O'Toole GA
J Bacteriol 2011 Sep;193(18):4685-98
PubMed ID: 21764921