Pseudomonas aeruginosa PAO1, PA2683.1 (tsi5)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2683.1
Name
tsi5
Synonym: rhsI1
Synonym: immunity protein RhsI1
Replicon chromosome
Genomic location 3031561 - 3031791 (- strand)
Comment76 aa immunity gene associated with rhsP1(PA2684)
Comment76 aa immunity gene associated with rhsP1(PA2684)

Cross-References

RefSeq
GI

Product

Feature Type CDS
Coding Frame 1
Product Name
Tsi5
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) 4.16
Kyte-Doolittle Hydrophobicity Value 0.597
Molecular Weight (kDa) 8758.4
Isoelectric Point (pI) 9.57

Subcellular localization

Individual Mappings
Localization Confidence PMID
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG008403 (1 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2683.1
Search term: tsi5
Search term: Tsi5

Human Homologs

References

The VgrG proteins are "à la carte" delivery systems for bacterial type VI effectors.
Hachani A, Allsopp LP, Oduko Y, Filloux A
J Biol Chem 2014 Jun 20;289(25):17872-84
PubMed ID: 24794869
Genetically distinct pathways guide effector export through the type VI secretion system.
Whitney JC, Beck CM, Goo YA, Russell AB, Harding BN, De Leon JA, Cunningham DA, Tran BQ, Low DA, Goodlett DR, Hayes CS, Mougous JD
Mol Microbiol 2014 May;92(3):529-42
PubMed ID: 24589350
RsmA and AmrZ orchestrate the assembly of all three type VI secretion systems in Pseudomonas aeruginosa.
Allsopp LP, Wood TE, Howard SA, Maggiorelli F, Nolan LM, Wettstadt S, Filloux A
Proc Natl Acad Sci U S A 2017 Jul 18;114(29):7707-7712
PubMed ID: 28673999