Strain |
Pseudomonas aeruginosa PA103 - Assembly GCF_000611975.2
GCF_000611975.2|latest |
Locus Tag |
PA103_3465
|
Name |
exoT
|
Replicon | scaffold-98 |
Genomic location | 4331 - 5704 (+ strand) |
RefSeq | WP_003114583.1 |
GI | 489205537 |
NCBI Locus Tag | PA103_3465 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
exoenzyme T
|
Synonyms |
ADP-ribosyltransferase |
Evidence for Translation | |
Charge (pH 7) | -8.32 |
Kyte-Doolittle Hydrophobicity Value | -0.313 |
Molecular Weight (kDa) | 48.5 |
Isoelectric Point (pI) | 5.66 |
Individual Mappings | |
Additional evidence for subcellular localization |
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
6GNN | TOXIN | 05/31/18 | Exoenzyme T from Pseudomonas aeruginosa in complex with human 14-3-3 protein beta, tetrameric crystal form bound to STO1101 | Homo sapiens; Pseudomonas aeruginosa PAO1 | 3.79 | X-RAY DIFFRACTION | 99.6 |
6JNP | TOXIN | 03/17/19 | Structure of ExoT-SpcS Complex from Pseudomonas aeruginosa in 2.2 Angstrom | Pseudomonas aeruginosa | 2.261 | X-RAY DIFFRACTION | 98.2 |
4JMF | TOXIN/CHAPERONE | 03/14/13 | Crystal structure of ExoT (residues 28 -77)- SpcS complex from Pseudomonas aeruginosa at 2.1 angstrom | Pseudomonas aeruginosa | 2.099 | X-RAY DIFFRACTION | 100.0 |
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group | |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA103_3465
Search term: exoT
Search term: exoenzyme T
|
ExoT of cytotoxic Pseudomonas aeruginosa prevents uptake by corneal epithelial cells.
Cowell BA, Chen DY, Frank DW, Vallis AJ, Fleiszig SM
Infect Immun 2000 Jan;68(1):403-6
PubMed ID: 10603417
|