Pseudomonas aeruginosa UCBPP-PA14, PA14_00910 (icmF1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_00910
Name
icmF1
Synonym: tssM1
Replicon chromosome
Genomic location 89166 - 92474 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 12 transposon mutants in orthologs
CommentHcp Secretion Island-I-encoded type VI secretion system (H1-T6SS)

Cross-References

RefSeq YP_788233.1
GI 116053797
Entrez 4380423
INSDC ABJ15033.1
NCBI Locus Tag PA14_00910
UniParc UPI0000E44883
UniProtKB Acc Q02V03
UniProtKB ID Q02V03_PSEAB
UniRef100 UniRef100_Q02V03
UniRef50 UniRef50_Q9I755
UniRef90 UniRef90_Q9I755

Product

Feature Type CDS
Coding Frame 1
Product Name
IcmF1
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) -6.61
Kyte-Doolittle Hydrophobicity Value -0.244
Molecular Weight (kDa) 121.5
Isoelectric Point (pI) 5.99

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 104 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000076 (865 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_00910
Search term: icmF1
Search term: IcmF1

Human Homologs

References

RsmA and AmrZ orchestrate the assembly of all three type VI secretion systems in Pseudomonas aeruginosa.
Allsopp LP, Wood TE, Howard SA, Maggiorelli F, Nolan LM, Wettstadt S, Filloux A
Proc Natl Acad Sci U S A 2017 Jul 18;114(29):7707-7712
PubMed ID: 28673999