Pseudomonas aeruginosa UCBPP-PA14, PA14_26880 (bvlR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_26880
Name
bvlR
Replicon chromosome
Genomic location 2338187 - 2339080 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 23 transposon mutants in orthologs

Cross-References

RefSeq YP_790297.1
GI 116050880
Entrez 4380924
INSDC ABJ12116.1
NCBI Locus Tag PA14_26880
UniParc UPI0000395F18
UniProtKB Acc Q02P39
UniProtKB ID Q02P39_PSEAB
UniRef100 UniRef100_S0IIE3
UniRef50 UniRef50_A9H9M3
UniRef90 UniRef90_A6V3L4

Product

Feature Type CDS
Coding Frame 1
Product Name
BvlR
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 1.23
Kyte-Doolittle Hydrophobicity Value -0.299
Molecular Weight (kDa) 33.7
Isoelectric Point (pI) 7.29

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 506 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000055 (3840 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_26880
Search term: bvlR
Search term: BvlR

Human Homologs

References

A new regulator of pathogenicity (bvlR) is required for full virulence and tight microcolony formation in Pseudomonas aeruginosa.
McCarthy RR, Mooij MJ, Reen FJ, Lesouhaitier O, O'Gara F
Microbiology (Reading) 2014 Jul;160(Pt 7):1488-1500
PubMed ID: 24829363