Pseudomonas aeruginosa UCBPP-PA14, PA14_37840 (sppD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag
PA14_37840
Name
sppD
Replicon chromosome
Genomic location 3374868 - 3376478 (- strand)
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq YP_791177.1
GI 116050010
Entrez 4382351
INSDC ABJ11246.1
NCBI Locus Tag PA14_37840
UniParc UPI000039697C
UniProtKB Acc Q02LK9
UniProtKB ID Q02LK9_PSEAB
UniRef100 UniRef100_S0I8Y5
UniRef50 UniRef50_P33916
UniRef90 UniRef90_Q9I254

Product

Feature Type CDS
Coding Frame 1
Product Name
ABC transporter ATP-binding protein, SppD
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) 17.42
Kyte-Doolittle Hydrophobicity Value -0.080
Molecular Weight (kDa) 59.3
Isoelectric Point (pI) 10.20

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003388 (303 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_37840
Search term: sppD

Human Homologs

Ensembl 86, assembly GRCh38.p7
ATP binding cassette subfamily B member 10 [Source:HGNC Symbol;Acc:HGNC:41]
E-value: 2.5e-20
Percent Identity: 31.3

Transposon Insertions in UCBPP-PA14

Transposon Insertions in Orthologs

Type Confirmed ISphoA/hah insertion site
Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag PA2061
Mutant ID UWGC: 46727
Genomic Position 2258358
Position in ORF 637(1611)
Reference 14617778
Type Confirmed ISlacZ/hah insertion site
Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag PA2061
Mutant ID UWGC: 8663
Genomic Position 2258553
Position in ORF 832(1611)
Reference 14617778

References

Swarming motility is modulated by expression of the putative xenosiderophore transporter SppR-SppABCD in Pseudomonas aeruginosa PA14.
Pletzer D(1,)(2), Braun Y(3), Weingart H(3).
Antonie Van Leeuwenhoek. 2016 Jun;109(6):737-53.
PubMed ID: 26995781