Strain |
Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest |
Locus Tag |
PA14_43040
|
Name |
hsiB2
Synonym: tssB2 |
Replicon | chromosome |
Genomic location | 3829090 - 3829596 (- strand) |
Transposon Mutants in orthologs | 6 transposon mutants in orthologs |
Comment | Hcp Secretion Island-II-encoded type VI secretion system (H2-T6SS) |
RefSeq | YP_791589.1 |
GI | 116049606 |
Entrez | 4382919 |
INSDC | ABJ10842.1 |
NCBI Locus Tag | PA14_43040 |
UniParc | UPI00003967E6 |
UniProtKB Acc | Q02KE7 |
UniProtKB ID | Q02KE7_PSEAB |
UniRef100 | UniRef100_Q02KE7 |
UniRef50 | UniRef50_B6EJ78 |
UniRef90 | UniRef90_W0YNN9 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
HsiB2
|
Synonyms |
hypothetical protein |
Evidence for Translation | |
Charge (pH 7) | -7.00 |
Kyte-Doolittle Hydrophobicity Value | -0.343 |
Molecular Weight (kDa) | 18.2 |
Isoelectric Point (pI) | 4.54 |
Individual Mappings | |
Additional evidence for subcellular localization |
Source 1 | |
Database | PseudoCAP |
Category | Hcp secretion island-2 encoded type VI secretion system (H2-T6SS) |
Evidence |
ECO:0000316
genetic interaction evidence used in manual assertion
|
Host Organism | Arabidopsis thaliana |
Notes | |
Infection model | Arabidopsis leaf infiltration model |
Reference | 19497948 |
Source 2 | |
Database | PseudoCAP |
Category | Hcp secretion island-2 encoded type VI secretion system (H2-T6SS) |
Evidence |
ECO:0000316
genetic interaction evidence used in manual assertion
|
Host Organism | Mus musculus |
Notes | |
Infection model | Mouse acute lung Infection model |
Infection model | Mouse burn Infection model |
Reference | 19497948 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 107 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000082 (1224 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA14_43040
Search term: hsiB2
Search term: HsiB2
|
Quorum sensing differentially regulates Pseudomonas aeruginosa type VI secretion locus I and homologous loci II and III, which are required for pathogenesis.
Lesic B, Starkey M, He J, Hazan R, Rahme LG
Microbiology (Reading) 2009 Sep;155(Pt 9):2845-2855
PubMed ID: 19497948
|
The second type VI secretion system of Pseudomonas aeruginosa strain PAO1 is regulated by quorum sensing and Fur and modulates internalization in epithelial cells.
Sana TG, Hachani A, Bucior I, Soscia C, Garvis S, Termine E, Engel J, Filloux A, Bleves S
J Biol Chem 2012 Aug 3;287(32):27095-105
PubMed ID: 22665491
|
RsmA and AmrZ orchestrate the assembly of all three type VI secretion systems in Pseudomonas aeruginosa.
Allsopp LP, Wood TE, Howard SA, Maggiorelli F, Nolan LM, Wettstadt S, Filloux A
Proc Natl Acad Sci U S A 2017 Jul 18;114(29):7707-7712
PubMed ID: 28673999
|
The archetype Pseudomonas aeruginosa proteins TssB and TagJ form a novel subcomplex in the bacterial type VI secretion system.
Lossi NS, Manoli E, Simpson P, Jones C, Hui K, Dajani R, Coulthurst SJ, Freemont P, Filloux A
Mol Microbiol 2012 Oct;86(2):437-56
PubMed ID: 22906320
|