Pseudomonas aeruginosa UCBPP-PA14, PA14_50680 (shaA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_50680
Name
shaA
Replicon chromosome
Genomic location 4502114 - 4502461 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14

Cross-References

RefSeq YP_792210.1
GI 116048988
Entrez 4384768
INSDC ABJ10224.1
NCBI Locus Tag PA14_50680
UniParc UPI00003965BF
UniProtKB Acc Q02IM6
UniProtKB ID Q02IM6_PSEAB
UniRef100 UniRef100_Q02IM6
UniRef50 UniRef50_Q02IM6
UniRef90 UniRef90_Q02IM6

Product

Feature Type CDS
Coding Frame 1
Product Name
ShaA
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 2.46
Kyte-Doolittle Hydrophobicity Value 0.687
Molecular Weight (kDa) 12.6
Isoelectric Point (pI) 9.63

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 219 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001021 (414 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_50680
Search term: shaA
Search term: ShaA

Human Homologs

References

Characterization of a multigene-encoded sodium/hydrogen antiporter (sha) from Pseudomonas aeruginosa: its involvement in pathogenesis.
Kosono S, Haga K, Tomizawa R, Kajiyama Y, Hatano K, Takeda S, Wakai Y, Hino M, Kudo T
J Bacteriol 2005 Aug;187(15):5242-8
PubMed ID: 16030218