Pseudomonas aeruginosa UCBPP-PA14, PA14_50710 (shaD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_50710
Name
shaD
Replicon chromosome
Genomic location 4503233 - 4504732 (- strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14

Cross-References

RefSeq YP_792213.1
GI 116048985
Entrez 4384765
INSDC ABJ10221.1
NCBI Locus Tag PA14_50710
UniParc UPI00003965BB
UniProtKB Acc Q02IM3
UniProtKB ID Q02IM3_PSEAB
UniRef100 UniRef100_S0J0Y6
UniRef50 UniRef50_B3PFD2
UniRef90 UniRef90_Q9I4R8

Product

Feature Type CDS
Coding Frame 1
Product Name
ShaD
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 9.63
Kyte-Doolittle Hydrophobicity Value 1.009
Molecular Weight (kDa) 52.3
Isoelectric Point (pI) 9.84

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 555 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001018 (533 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_50710
Search term: shaD
Search term: ShaD

Human Homologs

References

Characterization of a multigene-encoded sodium/hydrogen antiporter (sha) from Pseudomonas aeruginosa: its involvement in pathogenesis.
Kosono S, Haga K, Tomizawa R, Kajiyama Y, Hatano K, Takeda S, Wakai Y, Hino M, Kudo T
J Bacteriol 2005 Aug;187(15):5242-8
PubMed ID: 16030218