Pseudomonas aeruginosa UCBPP-PA14, PA14_58350 (dppA1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag
PA14_58350
Name
dppA1
Replicon chromosome
Genomic location 5195069 - 5196682 (+ strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 4 transposon mutants in orthologs

Cross-References

RefSeq YP_792841.1
GI 116052528
Entrez 4382618
INSDC ABJ13764.1
NCBI Locus Tag PA14_58350
UniParc UPI0000E44BE5
UniProtKB Acc Q02GU5
UniProtKB ID Q02GU5_PSEAB
UniRef100 UniRef100_S0IPR2
UniRef50 UniRef50_Q4KIC0
UniRef90 UniRef90_V6ALT5

Product

Feature Type CDS
Coding Frame 1
Product Name
dipeptide ABC transporter substrate-binding protein DppA1
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) 1.06
Kyte-Doolittle Hydrophobicity Value -0.469
Molecular Weight (kDa) 60.1
Isoelectric Point (pI) 7.28

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 560 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004084 (851 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_58350
Search term: dppA1

Transposon Insertions in UCBPP-PA14

Type MAR2xT7 transposon (wild type background) insertion site
Mutant ID PA14NR: 33142
Genomic Position 5195209
Position in ORF 141(1614)
Reference 16477005
Type MAR2xT7 transposon (wild type background) insertion site
Mutant ID PA14NR: 41807
Genomic Position 5196681
Position in ORF 1613(1614)
Reference 16477005

Transposon Insertions in Orthologs

Type mini-Tn5 lux transposon insertion site (Transcriptional fusion)
Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag PA4496
Mutant ID UBC: PAO1_lux_21_E1
Genomic Position 5033013
Position in ORF 1526(1614)
Reference 15805499
Type mini-Tn5 lux transposon insertion site (Transcriptional fusion)
Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag PA4496
Mutant ID UBC: PAO1_lux_46_H6
Genomic Position 5032954
Position in ORF 1467(1614)
Reference 15805499
Type ISphoA/hah insertion site
Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag PA4496
Mutant ID UWGC: 30225
Genomic Position 5032774
Position in ORF 1287(1614)
Reference 14617778
Type Confirmed ISphoA/hah insertion site
Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag PA4496
Mutant ID UWGC: 32242
Genomic Position 5032423
Position in ORF 936(1614)
Reference 14617778

References

High-throughput screening of dipeptide utilization mediated by the ABC transporter DppBCDF and its substrate-binding proteins DppA1-A5 in Pseudomonas aeruginosa.
Pletzer D(1), Lafon C(2), Braun Y(1), Köhler T(3), Page MG(4), Mourez M(2), Weingart H(1).
PLoS One. 2014 Oct 22;9(10):e111311.
PubMed ID: 25338022