Pseudomonas aeruginosa UCBPP-PA14, PA14_58490 (dppF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag
PA14_58490
Name
dppF
Replicon chromosome
Genomic location 5208616 - 5209587 (+ strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq YP_792851.1
GI 116052537
Entrez 4382627
INSDC ABJ13773.1
NCBI Locus Tag PA14_58490
UniParc UPI00003963B3
UniProtKB Acc Q02GT5
UniProtKB ID Q02GT5_PSEAB
UniRef100 UniRef100_A0A0C6EPY7
UniRef50 UniRef50_U4KA71
UniRef90 UniRef90_W0YZ53

Product

Feature Type CDS
Coding Frame 1
Product Name
dipeptide ABC transporter ATP-binding protein DppF
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) 10.73
Kyte-Doolittle Hydrophobicity Value -0.415
Molecular Weight (kDa) 36.4
Isoelectric Point (pI) 9.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004093 (545 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_58490
Search term: dppF

Human Homologs

Ensembl 86, assembly GRCh38.p7
ATP binding cassette subfamily B member 7 [Source:HGNC Symbol;Acc:HGNC:48]
E-value: 1.6e-22
Percent Identity: 33.8

Transposon Insertions in UCBPP-PA14

Type MAR2xT7 transposon (wild type background) insertion site
Mutant ID PA14NR: 46062
Genomic Position 5208916
Position in ORF 301(972)
Reference 16477005
Type MAR2xT7 transposon (wild type background) insertion site
Mutant ID PA14NR: 25289
Genomic Position 5209361
Position in ORF 746(972)
Reference 16477005

Transposon Insertions in Orthologs

Type mini-Tn5 lux transposon insertion site (Transcriptional fusion)
Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag PA4506
Mutant ID UBC: PAO1_lux_41_D4
Genomic Position 5045746
Position in ORF 719(972)
Reference 15805499
Type Confirmed ISlacZ/hah insertion site
Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag PA4506
Mutant ID UWGC: 4963
Genomic Position 5045640
Position in ORF 613(972)
Reference 14617778
Type Confirmed ISlacZ/hah insertion site
Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag PA4506
Mutant ID UWGC: 18549
Genomic Position 5045582
Position in ORF 555(972)
Reference 14617778

References

High-throughput screening of dipeptide utilization mediated by the ABC transporter DppBCDF and its substrate-binding proteins DppA1-A5 in Pseudomonas aeruginosa.
Pletzer D(1), Lafon C(2), Braun Y(1), Köhler T(3), Page MG(4), Mourez M(2), Weingart H(1).
PLoS One. 2014 Oct 22;9(10):e111311.
PubMed ID: 25338022