Pseudomonas aeruginosa UCBPP-PA14, PA14_61840

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag
PA14_61840
Name
Replicon chromosome
Genomic location 5514196 - 5514516 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14

Cross-References

RefSeq YP_793136.1
GI 116052819
Entrez 4385672
INSDC ABJ14055.1
NCBI Locus Tag PA14_61840
UniParc UPI0000E44C22
UniProtKB Acc Q02G00
UniProtKB ID Q02G00_PSEAB
UniRef100 UniRef100_S0J386
UniRef50 UniRef50_A6VCC3
UniRef90 UniRef90_A6VCC3

Product

Feature Type CDS
Coding Frame 1
Product Name
Antitoxin HigA
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) -5.29
Kyte-Doolittle Hydrophobicity Value -0.150
Molecular Weight (kDa) 11.2
Isoelectric Point (pI) 4.61

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 219 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004324 (358 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_61840
Search term: Antitoxin HigA

Transposon Insertions in UCBPP-PA14

Type MAR2xT7 transposon (wild type background) insertion site
Mutant ID PA14NR: 26343
Genomic Position 5514254
Position in ORF 59(306)
Reference 16477005

Transposon Insertions in Orthologs

References

The HigB/HigA toxin/antitoxin system of Pseudomonas aeruginosa influences the virulence factors pyochelin, pyocyanin, and biofilm formation.
Wood TL(1,)(2), Wood TK(1,)(3).
Microbiologyopen. 2016 Jun;5(3):499-511.
PubMed ID: 26987441