Strain |
Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest |
Locus Tag |
PA14_61840
|
Name |
|
Replicon | chromosome |
Genomic location | 5514196 - 5514516 (- strand) |
Transposon Mutants | 1 transposon mutants in UCBPP-PA14 |
RefSeq | YP_793136.1 |
GI | 116052819 |
Entrez | 4385672 |
INSDC | ABJ14055.1 |
NCBI Locus Tag | PA14_61840 |
UniParc | UPI0000E44C22 |
UniProtKB Acc | Q02G00 |
UniProtKB ID | Q02G00_PSEAB |
UniRef100 | UniRef100_S0J386 |
UniRef50 | UniRef50_A6VCC3 |
UniRef90 | UniRef90_A6VCC3 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
Antitoxin HigA
|
Synonyms |
virulence-associated protein |
Evidence for Translation | |
Charge (pH 7) | -5.29 |
Kyte-Doolittle Hydrophobicity Value | -0.150 |
Molecular Weight (kDa) | 11.2 |
Isoelectric Point (pI) | 4.61 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
7CSY | ANTITOXIN/DNA | 08/17/20 | Pseudomonas aeruginosa antitoxin HigA with higBA promoter | Pseudomonas aeruginosa PAO1; Pseudomonas aeruginosa UCBPP-PA14 | 2.29 | X-RAY DIFFRACTION | 98.0 |
7CSV | ANTITOXIN | 08/17/20 | Pseudomonas aeruginosa antitoxin HigA | Pseudomonas aeruginosa PAO1 | 1.71 | X-RAY DIFFRACTION | 98.0 |
6JPI | ANTITOXIN/DNA | 03/27/19 | Crystal structure of PA4674 in complex with its operator DNA (28bp) from Pseudomonas aeruginosa | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); SYNTHETIC CONSTRUCT | 3.143 | X-RAY DIFFRACTION | 98.0 |
6LB3 | ANTITOXIN/DNA | 11/13/19 | Crystal structure of PA4674 in complex with its operator DNA (18bp) from Pseudomonas aeruginosa | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); SYNTHETIC CONSTRUCT | 2.497 | X-RAY DIFFRACTION | 98.0 |
7CSW | ANTITOXIN/DNA | 08/17/20 | Pseudomonas aeruginosa antitoxin HigA with pa2440 promoter | Pseudomonas aeruginosa PAO1; Pseudomonas aeruginosa UCBPP-PA14 | 1.97 | X-RAY DIFFRACTION | 98.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 219 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG004324 (343 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA14_61840
Search term: Antitoxin HigA
|
The HigB/HigA toxin/antitoxin system of Pseudomonas aeruginosa influences the virulence factors pyochelin, pyocyanin, and biofilm formation.
Wood TL, Wood TK
Microbiologyopen 2016 Jun;5(3):499-511
PubMed ID: 26987441
|