Pseudomonas aeruginosa UCBPP-PA14, PA14_61840
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain | Pseudomonas aeruginosa UCBPP-PA14 |
| Locus Tag |
PA14_61840
|
| Name |
|
| Replicon | chromosome |
| Genomic location | 5514196 - 5514516 (- strand) |
| Transposon Mutants | 1 transposon mutants in UCBPP-PA14 |
Cross-References
| RefSeq | YP_793136.1 |
| GI | 116052819 |
| Entrez | 4385672 |
| INSDC | ABJ14055.1 |
| NCBI Locus Tag | PA14_61840 |
| UniParc | UPI0000E44C22 |
| UniProtKB Acc | Q02G00 |
| UniProtKB ID | Q02G00_PSEAB |
| UniRef100 | UniRef100_S0J386 |
| UniRef50 | UniRef50_A6VCC3 |
| UniRef90 | UniRef90_A6VCC3 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
Antitoxin HigA
|
| Evidence for Translation | |
| Charge (pH 7) | -5.29 |
| Kyte-Doolittle Hydrophobicity Value | -0.150 |
| Molecular Weight (kDa) | 11.2 |
| Isoelectric Point (pI) | 4.61 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 219 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group | POG004324 (352 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA14_61840
Search term: Antitoxin HigA
|
Transposon Insertions in UCBPP-PA14
| Type | MAR2xT7 transposon (wild type background) insertion site | |
| Mutant ID | PA14NR: 26343 | |
| Genomic Position | 5514254 | |
| Position in ORF | 59(306) | |
| Reference | 16477005 |
Transposon Insertions in Orthologs
References
|
The HigB/HigA toxin/antitoxin system of Pseudomonas aeruginosa influences the virulence factors pyochelin, pyocyanin, and biofilm formation.
Wood TL, Wood TK
Microbiologyopen 2016 Jun;5(3):499-511
PubMed ID: 26987441
|