Pseudomonas aeruginosa UCBPP-PA14, PA14_63910 (cntI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_63910
Name
cntI
Synonym: zrmD
Replicon chromosome
Genomic location 5695402 - 5696256 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 2 transposon mutants in orthologs
Commentpart of the Zur-regulated metallophore operon known as cntOLMI (PMID:29214991) or zrmABCD(PMID:28898501).

Cross-References

RefSeq YP_793300.1
GI 116052982
Entrez 4383303
INSDC ABJ14218.1
NCBI Locus Tag PA14_63910
UniParc UPI000045D498
UniProtKB Acc Q02FI6
UniProtKB ID Q02FI6_PSEAB
UniRef100 UniRef100_S0HUP3
UniRef50 UniRef50_Q9HUX6
UniRef90 UniRef90_Q9HUX6

Product

Feature Type CDS
Coding Frame 1
Product Name
CntI
Product Name Confidence: Class 3
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) 7.12
Kyte-Doolittle Hydrophobicity Value 1.172
Molecular Weight (kDa) 30.7
Isoelectric Point (pI) 9.65

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 247 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004465 (299 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_63910
Search term: cntI
Search term: CntI

Human Homologs

References

Growth of Pseudomonas aeruginosa in zinc poor environments is promoted by a nicotianamine-related metallophore.
Mastropasqua MC, D'Orazio M, Cerasi M, Pacello F, Gismondi A, Canini A, Canuti L, Consalvo A, Ciavardelli D, Chirullo B, Pasquali P, Battistoni A
Mol Microbiol 2017 Nov;106(4):543-561
PubMed ID: 28898501
Pseudomonas aeruginosa zinc uptake in chelating environment is primarily mediated by the metallophore pseudopaline.
Lhospice S, Gomez NO, Ouerdane L, Brutesco C, Ghssein G, Hajjar C, Liratni A, Wang S, Richaud P, Bleves S, Ball G, Borezée-Durant E, Lobinski R, Pignol D, Arnoux P, Voulhoux R
Sci Rep 2017 Dec 7;7(1):17132
PubMed ID: 29214991