Pseudomonas aeruginosa UCBPP-PA14, PA14_66140 (dnpA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_66140
Name
dnpA
Replicon chromosome
Genomic location 5891005 - 5892423 (- strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq YP_793471.1
GI 116053150
Entrez 4385504
INSDC ABJ14386.1
NCBI Locus Tag PA14_66140
UniParc UPI000045D4E5
UniProtKB Acc Q02F15
UniProtKB ID Q02F15_PSEAB
UniRef100 UniRef100_Q02F15
UniRef50 UniRef50_Q87VE8
UniRef90 UniRef90_Q9HUG3

Product

Feature Type CDS
Coding Frame 1
Product Name
de-N-acetylase involved in persistence, DnpA
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) 6.99
Kyte-Doolittle Hydrophobicity Value -0.270
Molecular Weight (kDa) 53.6
Isoelectric Point (pI) 8.61

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 9 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004610 (515 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_66140
Search term: dnpA

Human Homologs

References

A putative de-N-acetylase of the PIG-L superfamily affects fluoroquinolone tolerance in Pseudomonas aeruginosa.
Liebens V, Defraine V, Van der Leyden A, De Groote VN, Fierro C, Beullens S, Verstraeten N, Kint C, Jans A, Frangipani E, Visca P, Marchal K, Versées W, Fauvart M, Michiels J
Pathog Dis 2014 Jun;71(1):39-54
PubMed ID: 24692291