Pseudomonas aeruginosa UCBPP-PA14, PA14_70340 (sphB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag
PA14_70340
Name
sphB
Replicon chromosome
Genomic location 6272673 - 6273062 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14

Cross-References

RefSeq YP_793802.1
GI 116053475
Entrez 4385091
INSDC ABJ14711.1
NCBI Locus Tag PA14_70340
UniParc UPI0000E44C7F
UniProtKB Acc Q02E34
UniProtKB ID Q02E34_PSEAB
UniRef100 UniRef100_V6AP77
UniRef50 UniRef50_Q4KAC1
UniRef90 UniRef90_Q9HTM7

Product

Feature Type CDS
Coding Frame 1
Product Name
SphB
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) -1.72
Kyte-Doolittle Hydrophobicity Value -0.070
Molecular Weight (kDa) 13.5
Isoelectric Point (pI) 5.65

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 96 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004897 (814 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_70340
Search term: sphB
Search term: SphB

Transposon Insertions in UCBPP-PA14

Type MAR2xT7 transposon (wild type background) insertion site
Mutant ID PA14NR: 25595
Genomic Position 6272897
Position in ORF 225(390)
Reference 16477005

Transposon Insertions in Orthologs

References

Detection of host-derived sphingosine by Pseudomonas aeruginosa is important for survival in the murine lung.
LaBauve AE, Wargo MJ
PLoS Pathog. 2014 Jan;10(1):e1003889
PubMed ID: 24465209