Pseudomonas aeruginosa PA7, PSPA7_1407 (txcZ )

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
GCF_000017205.1|latest
Locus Tag
PSPA7_1407
Name
txcZ
Replicon chromosome
Genomic location 1424580 - 1425047 (- strand)

Cross-References

RefSeq YP_001346791.1
GI 152983864
Entrez 5354190
INSDC ABR81047.1
NCBI Locus Tag PSPA7_1407
UniParc UPI0000D737CA
UniProtKB Acc A6V156
UniProtKB ID A6V156_PSEA7
UniRef100 UniRef100_A6V156
UniRef50 UniRef50_A6V156
UniRef90 UniRef90_A6V156

Product

Feature Type CDS
Coding Frame 1
Product Name
TxcZ
Product Name Confidence: Class 1
Synonyms general secretion pathway protein M
Evidence for Translation
Charge (pH 7) 0.72
Kyte-Doolittle Hydrophobicity Value -0.153
Molecular Weight (kDa) 17102.4
Isoelectric Point (pI) 7.81

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 3 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG024009 (17 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_1407
Search term: txcZ
Search term: TxcZ

Human Homologs

References

Txc, a new type II secretion system of Pseudomonas aeruginosa strain PA7, is regulated by the TtsS/TtsR two-component system and directs specific secretion of the CbpE chitin-binding protein.
Cadoret F, Ball G, Douzi B, Voulhoux R
J Bacteriol 2014 Jul;196(13):2376-86
PubMed ID: 24748613