Pseudomonas aeruginosa PA7, PSPA7_1414 (txcS )

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
GCF_000017205.1|latest
Locus Tag
PSPA7_1414
Name
txcS
Synonym: gspF3
Replicon chromosome
Genomic location 1428931 - 1430148 (- strand)

Cross-References

RefSeq YP_001346798.1
GI 152985154
Entrez 5355269
NCBI Locus Tag PSPA7_1414

Product

Feature Type CDS
Coding Frame 1
Product Name
TxcS
Product Name Confidence: Class 1
Synonyms general secretion pathway protein F
Evidence for Translation
Charge (pH 7) 17.87
Kyte-Doolittle Hydrophobicity Value 0.312
Molecular Weight (kDa) 43.7
Isoelectric Point (pI) 11.40

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 401 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG024016 (5 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_1414
Search term: txcS
Search term: TxcS

Human Homologs

References

Txc, a new type II secretion system of Pseudomonas aeruginosa strain PA7, is regulated by the TtsS/TtsR two-component system and directs specific secretion of the CbpE chitin-binding protein.
Cadoret F, Ball G, Douzi B, Voulhoux R
J Bacteriol 2014 Jul;196(13):2376-86
PubMed ID: 24748613