Pseudomonas aeruginosa PA7, PSPA7_1417 (txcP )

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
GCF_000017205.1|latest
Locus Tag
PSPA7_1417
Name
txcP
Replicon chromosome
Genomic location 1433524 - 1434036 (- strand)

Cross-References

RefSeq YP_001346801.1
GI 152984699
Entrez 5356212
INSDC ABR81882.1
NCBI Locus Tag PSPA7_1417
UniParc UPI00015774E8
UniProtKB Acc A6V166
UniProtKB ID A6V166_PSEA7
UniRef100 UniRef100_A6V166
UniRef50 UniRef50_A6V166
UniRef90 UniRef90_A6V166

Product

Feature Type CDS
Coding Frame 1
Product Name
TxcP
Product Name Confidence: Class 1
Synonyms outer membrane secretion protein P
Evidence for Translation
Charge (pH 7) 5.19
Kyte-Doolittle Hydrophobicity Value 0.178
Molecular Weight (kDa) 17728.3
Isoelectric Point (pI) 11.09

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 2 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG024019 (16 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_1417
Search term: txcP
Search term: TxcP

Human Homologs

References

Txc, a new type II secretion system of Pseudomonas aeruginosa strain PA7, is regulated by the TtsS/TtsR two-component system and directs specific secretion of the CbpE chitin-binding protein.
Cadoret F, Ball G, Douzi B, Voulhoux R
J Bacteriol 2014 Jul;196(13):2376-86
PubMed ID: 24748613