Pseudomonas aeruginosa PA7, PSPA7_1420 (ttsS )

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
GCF_000017205.1|latest
Locus Tag
PSPA7_1420
Name
ttsS
Replicon chromosome
Genomic location 1436301 - 1439900 (- strand)

Cross-References

RefSeq YP_001346804.1
GI 152983965
Entrez 5355023
INSDC ABR81148.1
NCBI Locus Tag PSPA7_1420
UniParc UPI0000D73908
UniProtKB Acc A6V169
UniProtKB ID A6V169_PSEA7
UniRef100 UniRef100_A6V169
UniRef50 UniRef50_A6V169
UniRef90 UniRef90_A6V169

Product

Feature Type CDS
Coding Frame 1
Product Name
TtsS
Product Name Confidence: Class 1
Synonyms sensory box histidine kinase/response regulator
Evidence for Translation
Charge (pH 7) -5.84
Kyte-Doolittle Hydrophobicity Value -0.235
Molecular Weight (kDa) 132288.2
Isoelectric Point (pI) 6.61

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 619 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG019146 (61 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_1420
Search term: ttsS
Search term: TtsS

Human Homologs

References

Txc, a new type II secretion system of Pseudomonas aeruginosa strain PA7, is regulated by the TtsS/TtsR two-component system and directs specific secretion of the CbpE chitin-binding protein.
Cadoret F, Ball G, Douzi B, Voulhoux R
J Bacteriol 2014 Jul;196(13):2376-86
PubMed ID: 24748613