Pseudomonas aeruginosa PA7, PSPA7_1421 (ttsR )

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
GCF_000017205.1|latest
Locus Tag
PSPA7_1421
Name
ttsR
Replicon chromosome
Genomic location 1439897 - 1440538 (- strand)

Cross-References

RefSeq YP_001346805.1
GI 152984530
Entrez 5358784
NCBI Locus Tag PSPA7_1421

Product

Feature Type CDS
Coding Frame 1
Product Name
TtsR
Product Name Confidence: Class 1
Synonyms putative two-component response regulator
Evidence for Translation
Charge (pH 7) 5.58
Kyte-Doolittle Hydrophobicity Value 0.064
Molecular Weight (kDa) 23.3
Isoelectric Point (pI) 9.21

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 478 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001606 (736 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_1421
Search term: ttsR
Search term: TtsR

Human Homologs

References

Txc, a new type II secretion system of Pseudomonas aeruginosa strain PA7, is regulated by the TtsS/TtsR two-component system and directs specific secretion of the CbpE chitin-binding protein.
Cadoret F, Ball G, Douzi B, Voulhoux R
J Bacteriol 2014 Jul;196(13):2376-86
PubMed ID: 24748613