Pseudomonas aeruginosa PA7, PSPA7_6249 (dprE2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
Locus Tag
PSPA7_6249
Name
dprE2
Replicon chromosome
Genomic location 6462100 - 6462837 (+ strand)

Cross-References

RefSeq YP_001351560.1
GI 152986072
Entrez 5358484
INSDC ABR83255.1
NCBI Locus Tag PSPA7_6249
UniParc UPI0000D727DE
UniProtKB Acc A6VES5
UniProtKB ID A6VES5_PSEA7
UniRef100 UniRef100_A6VES5
UniRef50 UniRef50_Q3J9T4
UniRef90 UniRef90_A6VES5

Product

Feature Type CDS
Coding Frame 1
Product Name
DprE2
Product Name Confidence: Class 2
CommentInvolved in the synthesis of D-arabinofuranose, a sugar that is attached to the type IV pilins of PA7 and related strains, as well as in some other Pseudomonads.
Evidence for Translation
Charge (pH 7) 5.86
Kyte-Doolittle Hydrophobicity Value 0.248
Molecular Weight (kDa) 26.3
Isoelectric Point (pI) 9.49

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 588 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG019261 (27 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_6249
Search term: dprE2
Search term: DprE2

References

Pseudomonas aeruginosa D-arabinofuranose biosynthetic pathway and its role in type IV pilus assembly.
Harvey H, Kus JV, Tessier L, Kelly J, Burrows LL
J. Biol. Chem. 2011 Aug;286(32):28128-37
PubMed ID: 21676874