Pseudomonas aeruginosa PAO1, PA3865.1

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3865.1
Name
Replicon chromosome
Genomic location 4327359 - 4327697 (- strand)
CommentOriginally characterized using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer. Confirmed using RT-PCR (PMID:24291602).

Cross-References

RefSeq
GI

Product

Feature Type CDS
Coding Frame 1
Product Name
pyocin S4 immunity protein
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Translation confirmed using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -1.53
Kyte-Doolittle Hydrophobicity Value -0.172
Molecular Weight (kDa) 12.3
Isoelectric Point (pI) 5.75

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG008414 (3 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3865.1

Human Homologs

References

The soluble pyocins S2 and S4 from Pseudomonas aeruginosa bind to the same FpvAI receptor.
Elfarash A, Wei Q, Cornelis P
Microbiologyopen 2012 Sep;1(3):268-75
PubMed ID: 23170226
LTQ-XL mass spectrometry proteome analysis expands the Pseudomonas aeruginosa AmpR regulon to include cyclic di-GMP phosphodiesterases and phosphoproteins, and identifies novel open reading frames.
Kumari H, Murugapiran SK, Balasubramanian D, Schneper L, Merighi M, Sarracino D, Lory S, Mathee K
J Proteomics 2014 Jan 16;96:328-342
PubMed ID: 24291602