Pseudomonas aeruginosa LESB58, PALES_11111 (dauA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa LESB58
GCF_000026645.1|latest
Locus Tag
PALES_11111
Name
dauA
Replicon chromosome
Genomic location 1205089 - 1206216 (- strand)

Cross-References

RefSeq YP_002438717
GI 218889853
Entrez 7175950

Product

Feature Type CDS
Coding Frame 1
Product Name
FAD-dependent catabolic D-arginine dehydrogenase, DauA
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -12.29
Kyte-Doolittle Hydrophobicity Value -0.138
Molecular Weight (kDa) 40.6
Isoelectric Point (pI) 5.11

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6P9D FLAVOPROTEIN, Oxidoreductase 06/10/19 Crystal Structure of Pseudomonas aeruginosa D-Arginine Dehydrogenase Y249F variant with FAD - Yellow fraction Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.329 X-RAY DIFFRACTION 99.2
3NYC OXIDOREDUCTASE 07/14/10 Crystal Structure of Pseudomonas aeruginosa D-Arginine Dehydrogenase Pseudomonas aeruginosa 1.06 X-RAY DIFFRACTION 99.5
7RDF FLAVOPROTEIN 07/09/21 Crystal structure of Pseudomonas aeruginosa D-Arginine Dehydrogenase Y249F co-crystallized in the presence of D-arginine Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.29 X-RAY DIFFRACTION 99.2
3NYE OXIDOREDUCTASE 07/14/10 Crystal Structure of Pseudomonas aeruginosa D-Arginine Dehydrogenase in Complex with Imino-Arginine Pseudomonas aeruginosa 1.3 X-RAY DIFFRACTION 99.5
6PLD FLAVOPROTEIN 06/30/19 Crystal Structure of Pseudomonas aeruginosa D-Arginine Dehydrogenase Y249F variant with 6-OH-FAD - Green fraction Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.55 X-RAY DIFFRACTION 99.2
3SM8 OXIDOREDUCTASE 06/27/11 Crystal Structure of Pseudomonas aeruginosa D-Arginine Dehydrogenase in Complex with an (N5) Flavin Adduct Pseudomonas aeruginosa 1.07 X-RAY DIFFRACTION 99.5
3NYF OXIDOREDUCTASE 07/15/10 Crystal Structure of Pseudomonas aeruginosa D-Arginine Dehydrogenase in Complex with Imino-Histidine Pseudomonas aeruginosa 1.3 X-RAY DIFFRACTION 99.5

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 171 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001806 (437 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PALES_11111
Search term: dauA

Human Homologs

References

Arginine racemization by coupled catabolic and anabolic dehydrogenases.
Li C, Lu CD
Proc Natl Acad Sci U S A 2009 Jan 20;106(3):906-11
PubMed ID: 19139398