Pseudomonas aeruginosa PAO1, PA4674.1 (higB)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
| Locus Tag |
PA4674.1
|
| Name |
higB
|
| Replicon | chromosome |
| Genomic location | 5242571 - 5242849 (- strand) |
Cross-References
| RefSeq | |
| GI |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
HigB
|
| Evidence for Translation | |
| Charge (pH 7) | 1.65 |
| Kyte-Doolittle Hydrophobicity Value | -0.421 |
| Molecular Weight (kDa) | 10.6 |
| Isoelectric Point (pI) | 8.25 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Pathogen Association Analysis
| Results | Analysis not done |
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group | |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA4674.1
Search term: higB
Search term: HigB
|
Human Homologs
References
|
The HigB/HigA toxin/antitoxin system of Pseudomonas aeruginosa influences the virulence factors pyochelin, pyocyanin, and biofilm formation.
Wood TL, Wood TK
Microbiologyopen 2016 Jun;5(3):499-511
PubMed ID: 26987441
|