Pseudomonas aeruginosa PAO1, PA5161 (rmlB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5161
Name
rmlB
Replicon chromosome
Genomic location 5810281 - 5811339 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1

Cross-References

RefSeq NP_253848.1
GI
Entrez 879982
GenBank AAG08546.1
INSDC AAG08546.1
NCBI Locus Tag PA5161
protein_id(GenBank) gb|AAG08546.1|AE004929_1|gnl|PseudoCAP|PA5161
UniParc UPI00000DCCF6
UniProtKB Acc Q9HU24
UniProtKB ID Q9HU24_PSEAE
UniRef100 UniRef100_W0YYT3
UniRef50 UniRef50_P55294
UniRef90 UniRef90_A6VDT2

Product

Feature Type CDS
Coding Frame 1
Product Name
dTDP-D-glucose 4,6-dehydratase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -7.96
Kyte-Doolittle Hydrophobicity Value -0.406
Molecular Weight (kDa) 39.5
Isoelectric Point (pI) 5.90

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 644 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004752 (533 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5161
Search term: rmlB

Human Homologs

References

Purification, characterization and HPLC assay of Salmonella glucose-1-phosphate thymidylyl-transferase from the cloned rfbA gene.
Lindquist L, Kaiser R, Reeves PR, Lindberg AA
Eur J Biochem 1993 Feb 1;211(3):763-70
PubMed ID: 8382158